Ashwell receptor plays key role in lowering coagulation abnormalities during illness and sepsis In research that solves the longest-standing up mystery in glycobiology – a field that studies complicated sugar chains called glycans – researchers at the University of California, San Diego School of Medicine can see a molecule in the liver of all animals, called the Ashwell receptor, is crucial in helping the body fight off the unusual and lethal blood clotting due to bacterial infection.The nanoparticle is delicate to oxidative tension, which happens in atherosclerosis and provides been associated with patients who have an increased prevalence of coronary attack and stroke. Using an MRI scan, the experts can see how energetic the nanoparticle is, which will indicate if the plaque is steady. ‘A stroke or a coronary attack doesn't necessarily arrive when a plaque completely blocks the blood circulation through an artery,’ Doiron explains. ‘What goes on may be the plaque ruptures and the gunk that underlies the plaque can be exposed to bloodstream and a clot forms. The clot builds quickly – on one hour time scale instead of over years – and the clot can develop there until it blocks movement, or it could dislodge and block stream else somewhere.